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Title   후두암 , 식도암 및 위암이 동시에 병발한 삼중복암 1 예 ( A Case of Synchronous Triple Primary Cancers in Larynx , Esophageu , and Stomach )
Publicationinfo   1996 Jan; 028(05): 888-897.
Key_word   Multiple primary malignant neoplasms, Larynx, Esophagus, Stomach
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Abstract   Multiple primary cancers can occur in up to 20% of primary aerodigestive tract cancer patients. The multiplicity of cancer in aerodigestive tract suggests that the exposure to common carcinogen may be the cause of multiplicity(field cancerization). Continuous alcohol drinking and smoking are considered to be the major factors in development of multiple cancers. Also, high frequency of genetic alterations in multiple primary cancer patients implys that the genetic instability such as replication error or mutation of tumor suppressor gene may play a role in the development of multiple primary cancers. We report a case of a 61 year-old man who had triple synchronous cancers in larynx, esophagus, and stomach. He was a heavy smoker of 30-pack-years and a heavy drinker. Pathological examination showed squamous cell carcinoma of larynx and esophagus, and adenocarrinoma of stomach, respectively.
저 자   권교선(Gyo Seon Kwun),김경태(Kyung Tae Kim),김용조(Yong Cho Kim),성주병(Ju Byeung Sung),이영우(Young Wo Lee),장은정(Eun Jung Jang),류백렬(Baek Yeol Ryoo),김태유(Tae You Kim),임영혁(Young Hyuck Im),강윤구(Yoon Koo Kang),이승숙(Seung sook Lee),이진오(Jim Oh Lee),강태웅(Tae Woong Kang)